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What is a stye?
A stye – also called a hordeolum (pronounced hor-dee-Oh-lum)- often appears as a red sore lump near the edge of the eyelid. It is usually caused by a bacterial infection. A stye will develop at the base of an eyelash if the eylash follicle (root) is infected. This is usually called an external hordeolum.

A stye will also develop if there is an infection in one of the tiny lubricating oil glands (called meibomian glands) inside or under the eyelid. When this occurs, it is usually called an internal hordeolum. A stye can also be caused by widespread inflammation (swelling) of the eyelid from blepharitis, a condition that affects the eyelid margins.
What is a chalazion?
A chalazion (pronounced kuh-LAY-zee-un) is an enlargement of an oil-producing gland in the eylid called the meibomian gland. It forms when the gland opening becomes clogged with oil secrections. It is not caused by an infection from bacteria, and it is not cancerous.

If an internal hordeolum doesn’t drain and heal, it can turn into a chalazion. Unlike a stye, a chalazion in usually painless.
What is the difference between a chalazion and a stye?
A chalazion is sometimes confused with a stye, which also appears as a lump on the eyelid. A stye is a red, sore lump near the edge of the eyelid caused by an infected eyelash follicle. Chalazia tend to develop farther from the edge of the eyelid than styes.
In some situations it may be difficult to distinguish between a chalazion and stye.

What are the symptoms of stye and chalazion?
Symptoms of a stye at first generally include eyelid tenderness and redness in the affected area, with irritation and scratchiness in the eye. Further symptoms of a stye include:
  • A red bump along the edge of the eyelid at the base of the eyelashes, usually with a small pus spot in the center
  • A feeling as if something is in your eye
  • Sensitivity to light
  • Crusting along the eyelid margin
  • Tearing

About 25% of chalazia have no symptoms and will disappear without any treatment. Sometimes, however, a chalazion may become red, swollen and tender. A larger chalazion may also cause blurred vision by distorting the shape of the eye. Occasionally, a chalazion can cause the entire eyelid to swell suddenly.

How are styes and chalazia treated?
It is important not to squeeze or try to pop a chalazion or stye. This may spread the infection into the surrounding eyelid tissue.

Symptoms of a stye or chalazion are treated with one or more of the following methods:

Warm Compresses. Warm compresses help to clear the clogged gland. Soak a clean washcloth in hot water and apply the cloth to the lid for 10 to 15 minutes, three to five times a day until the stye or chalazion is gone. You should repeatedly soak the cloth in hot water to keep it warm. The warm compress should allow the clogged gland to open and drain white or yellow discharge. If the gland opens, gently massage around the stye, or chalazion, to help it drain.

Antibiotic Ointments. An antibiotic ointment may be prescribed if bacteria infect the stye or chalazion.

Steroid Injections. A steroid (cortisone) injection is sometimes used to reduce inflammation of a chalazion.

Surgical Removal. If a large stye or chalazion does not respond to other treatments or affects vision, your ophthalmologist may drain it surgically. The procedure is usually performed under local anesthesia in your eye doctor’s office.

Chalazia and styes usually respond well to treatment, although some people tend to have them recur. If a chalazion comes back in the same place, your ophthalmologist may suggest a biopsy (where a tiny piece of tissue is surgically removed and studied) to rule out more serious problems.

Don’t wear eye makeup or contact lenses until after the stye or chalazion heals.

- American Academy of Ophthalmology
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